A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging.
نویسندگان
چکیده
We report a novel ruthenium(II) complex for selective release of the imidazole-based drug econazole. While the complex is highly stable and luminescent in the dark, irradiation with green light induces release of one of the econazole ligands, which is accompanied by a turn-off luminescence response and up to a 34-fold increase in cytotoxicity towards tumour cells.
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عنوان ژورنال:
- Chemical communications
دوره 51 74 شماره
صفحات -
تاریخ انتشار 2015